Not Yet RecruitingNot Applicable

The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage

United States85 participantsStarted 2025-11-01

Plain-language summary

The study will pertain to investigating the impact of high vs low IOP on the intraoperative experience and comfort for the patient and surgeon. Our hypothesis is that operating at a more physiological IOP using Unity VCS/CS and Centurion with Active Sentry at a higher, or more traditional IOP will result in significantly less discomfort/pain as assessed by the decreased need for rescue medication and lower VAS scores.

Who can participate

Age range60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Subjects who will require bilateral cataract surgery will be considered. Evaluations will occur in the clinic of the Principal Investigator (PI) Matthew Rauen, MD at the Wolfe Eye Clinic. Inclusion Criteria: * Visually significant cataract 2-3+ undergoing uncomplicated cataract surgery with similar cataract grade in both eyes * Unremarkable ocular health but inclusive of early AMD Exclusion Criteria: * H/o ocular surgery including corneal refractive surgery * Compromised zonular integrity or stability * Uncontrolled diabetes and diabetic retinopathy * Small pupils * H/o systemic inflammatory disease/uveitis * H/o chronic pain medications (including narcotics) and benzodiazepine usage * Abnormal liver or renal function

What they're measuring

Rescue Medication

Timeframe: During cataract surgery

Trial details

NCT IDNCT07223866

SponsorMatthew Rauen

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-11-01

Contact for this trial

Robyn Kohler, RN

515-223-8685 rkohler@wolfeclinic.com

View on ClinicalTrials.gov More Cataract and IOL Surgery trials