RecruitingNot Applicable

NIRS Monitoring in the NICU and AKI

United States100 participantsStarted 2025-11

Plain-language summary

The primary objective of this study is to describe the pattern of renal tissue oxygen saturation (SrSO2) using near-infrared spectroscopy (NIRS) in premature infants \<30 weeks gestational age. The secondary objective of this study is to evaluate prenatal and postnatal risk factors for acute kidney injury (AKI) in premature infants \<30 weeks gestational age. The investigators will also compare various rates of complications including death, length-of-stay, and prolonged duration of mechanical ventilation, among others.

Who can participate

Age range24 Weeks – 30 Weeks

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Any neonate less than 30 weeks in gestational age * Willingness and capacity of both adult parents/guardians to sign consent Exclusion Criteria: * An infant with known congenital anomalies of the kidney (i.e., grade 4 or 5 vesicoureteral reflux (VUR), posterior urethral valves, moderate or severe hydronephrosis, autosomal recessive polycystic kidney disease (ARPKD), bilateral renal agenesis or dysplasia) * Age \>30 weeks gestational age * Age \<24 weeks and \<500 grams (will be excluded due to sensitivity of skin in this vulnerable population). * Clinician's decision that NIRS is not suitable due to the patient's clinical condition

What they're measuring

Average NIRS Value (SrSO2)

Timeframe: Up to Day-of-life 7

Trial details

NCT IDNCT07222722

SponsorNYU Langone Health

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-04-01

Contact for this trial

Jordan Nelson, MD

3478223664 Jordan.nelson@nyulangone.org

View on ClinicalTrials.gov More Acute Kidney Injury (AKI) trials