RecruitingNot Applicable

Preoperative Opioid Tapering Before Spine Surgery

United States45 participantsStarted 2025-12-01

Plain-language summary

This is a pilot study in which patients taking opioids chronically who are scheduled for spine surgery at least 4 weeks in advance will be randomly assigned to one of two groups: opioid tapering with education alone or opioid tapering with education plus cognitive behavioral therapy (CBT). The primary objective is to determine the proportion of each group that is successful in achieving their opioid tapering goals by the time of surgery.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion: * at least 18 years old * scheduled for major spine surgery (i.e. at least 1 level of fusion) with hospital admission of at least one night * scheduled for spine surgery at least 4 weeks ahead of time * takes between 40 and 200 oral morphine equivalents daily Exclusion: * inability to use a computer or tablet for telemedicine encounters * non-English-speaking * inability to complete assessments * positive screen on the Columbia Suicide Screening Assessment

What they're measuring

proportion that achieved opioid tapering goal

Timeframe: Perioperative prior to surgery (postoperative day 0)

Trial details

NCT IDNCT07221786

SponsorThomas Jefferson University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12-01

Contact for this trial

Eric Schwenk, MD

267-239-3319 eric.schwenk@jefferson.edu

View on ClinicalTrials.gov More Opioid Consumption, Postoperative trials