Active — Not RecruitingPhase 3

PREVENT HPV -Related Cancers Trial

United States1,455 participantsStarted 2025-10-09

Plain-language summary

This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West. Once implemented into practice, our intervention could significantly reduce disparities in the burden of HPV-associated cancers among rural populations in the United States. The proposed study will assess the effectiveness of a clinic-based behavioral outreach intervention to increase HPV vaccination rates at community clinics in rural counties. The intervention consists of communication and engagement strategies delivered within routine care settings and is designed to pose no more than minimal risk to participants.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Parents/Caregivers (P/C) of children/adolescents (C/A) ages 9-17 years of age (i.e., age-eligible for HPV vaccination); * P/C with active clinic patients (i.e., have been seen in the clinic in the last 12 months); and * P/C who speak either English or Spanish. Exclusion Criteria: * P/C of C/A with previous excluding HPV vaccination history (e.g., completed vaccination, or not due); * P/C of C/A with clinical conditions that influence the CDC HPV vaccination recommendations (e.g., pregnancy); * P/C of C/A with other factors that would influence CDC HPV recommendations; and * P/C that does not speak Spanish or English.

What they're measuring

Intervention Reach: Vaccination Next Step Initiation (Next HPV dose completion)

Timeframe: 6 Months

Trial details

NCT IDNCT07217145

SponsorUniversity of Utah

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-02-01

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