This is a research study on human exercise that will investigate the immune system response post-exercise and how it relates to Delayed Onset Muscle Soreness (DOMS), and possible causes for DOMS. Blood draws (10mL) will be obtained at 5 timepoints: Baseline before intervention, day of exercise immediately following exercise, and post-exercise days 1, 2 and 4. Point of care lactate levels obtained before and after exercise. Subjective pain scores recorded daily starting immediately after after exercise.
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Mean change from baseline in phosphorylation markers in the Janus kinase/signal transducer and activator of transcription (JAK/STAT) and Toll-like Receptor (TLR)-pathway in immune cell populations
Timeframe: From enrollment to 5 days after the end of treatment