Active — Not RecruitingNot Applicable

A Clinical Study to Evaluate the Stain Reduction Efficacy of a Non-Fluoride Tooth Whitening Dentifrice Containing Nano-Hydroxyapatite (nHAP) and a High Cleaning Silica Abrasive System Compared to a Commercial Fluoride Non-Whitening Dentifrice as a Negative Control

India120 participantsStarted 2025-09-01

Plain-language summary

To determine whether brushing with a non-fluoride tooth whitening dentifrice containing nHAP and a high cleaning silica system produces a greater level of stain reduction as indicated by the Modified Lobene Stain Index (MLSI) for the overall tooth surfaces than brushing with a commercial fluoride toothpaste for a period of 2 weeks.

Who can participate

Age range18 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Good oral health with 16 natural teeth including 11 of the 12 anterior teeth.
✓. All facial surfaces gradable with no large restorations as judged by the investigator or dental assessor.

Exclusion criteria

✕. Participation in another clinical study or receipt of an investigational drug within 30 days of the screening visit.
✕. Previous participation in this study.

What they're measuring

WHITENING

Timeframe: 2 WEEKS

TOOTH COLOR

Timeframe: 2 WEEKS

Trial details

NCT IDNCT07214038

SponsorBoka LLC

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2025-10-01

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