This study investigated the adjunctive effects of diode laser therapy in smokers with severe periodontitis. Thirty-three patients were randomized to non-surgical periodontal therapy (SRP) with or without diode laser. Clinical parameters and salivary oxidative stress markers (MDA, 8-OHdG) were assessed at baseline, 1, and 3 months. Both groups showed improvements, but SRP+DL resulted in significantly greater reductions in deep pockets, PISA, PESA, PI, and MDA at 3 months. These findings suggest that diode laser therapy may enhance conventional treatment by improving clinical outcomes and reducing oxidative stress in smokers with severe periodontitis.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Probing Pocket Dept (PPD)
Timeframe: Through study completion, an average of 3 months.
Periodontal Epithelial Surface Area (PESA)
Timeframe: Through study completion, an average of 3 months.
Periodontal Inflamed Surface Area (PISA)
Timeframe: Through study completion, an average of 3 months.
Salivary Malondialdehyde Levels
Timeframe: Through study completion, an average of 3 months.
Salivary 8-hydroxy-2'-deoxyguanosine Levels
Timeframe: Through study completion, an average of 3 months.
PPD ≥4 mm, site-specific PPD (ssPPD)
Timeframe: Through study completion, an average of 3 months.
PPD ≥4 mm, site spesific CAL (ssCAL)
Timeframe: Through study completion, an average of 3 months.
PPD ≥4 mm, site-specific PISA (ssPISA)
Timeframe: Through study completion, an average of 3 months.
PPD ≥4 mm, site-specific PESA (ssPESA)
Timeframe: Through study completion, an average of 3 months.