High Dose Dexamethasone to Reduce Postoperative Pain After Video-Assisted Thoracoscopic Surgery Lobectomy /Segmentectomy

Inclusion Criteria: * Age ≥ 18 year * Able to understand written and spoken Danish language * PCS ≥20 * Signed written informed consent form. * Patient planned to elective VATS lobectomy/segmentectomy Exclusion Criteria: * Patients undergoing systemic glucocorticoid or other immunosuppressive therapies, ex-cluding inhaled steroids. * Individuals with diabetes requiring insulin treatment. * Pregnant or breastfeeding patients. * Patients with known allergies to the study drug. * Individuals with mental disabilities that may impair their capacity to provide informed consent or compromise the validity of data collection. * Patients with diagnosed schizophrenia, active psychosis, bipolar disorder, or a history of ongoing treatment with antipsychotic and/or antidepressant medications. * Individuals with altered pain perception due to other conditions or injuries, such as spi-nal cord or brain injuries, severe polyneuropathies, or neurological disorders. * Regular users of opioid medications. * Patients requiring reoperation within the first two postoperative days. * Individuals undergoing conversion to a surgical procedure other than VATS lobecto-my/segmentectomy.