CompletedNot Applicable

Axillary Nodal Burden in HER2+ and TNBC

South Korea1,571 participantsStarted 2025-06-01

Plain-language summary

This study aimed to evaluated rates of pathologic axillary nodal metastasis in patients with with early-stage HER2-positive BC or TNBC who had clinically node-negative status on preoperative ultrasonography and underwent upfront breast-conserving surgery (BCS) with axillary surgery. In addition, this study aimed to identify subgroups in which SLNB omission may be feasible.

Who can participate

Age range19 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * HER2-positive breast cancer or TNBC * Patients who received upfront breast conserving surgery with axillary surgery * Patients who had a clinically axillary node negative disease Exclusion Criteria: * Patients who underwent mastectomy * Absence of axillary nodal assessment on ultrasonography * Patients who underwent mastectomy * Patients who underwent mastectomy

What they're measuring

Pathologic axillary lymph node metastasis rate

Timeframe: Immediately after surgery

Trial details

NCT IDNCT07211451

SponsorGangnam Severance Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-08-31

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