Active — Not RecruitingNot Applicable

Radiographic and Histomorphometric Assessment of Anterior Horizontal Maxillary Bone Augmentation Using Autogenous and Bovine Sticky Bone Versus Autogenous and Bovine Bone Shell Technique (Khoury): A Randomized Comparative Clinical Trial

Egypt30 participantsStarted 2025-07-30

Plain-language summary

This clinical trial aims to compare two bone augmentation techniques for patients with anterior horizontal maxillary bone defects: Autogenous and Bovine Sticky Bone Technique using S1 Bovine Bone Graft Autogenous and Bovine Bone Shell Technique (Khoury Technique). The study will evaluate the amount of bone gain and the quality of bone formation after six months using radiographic (CBCT) and histomorphometric analysis. Patients will be randomly assigned to one of the two groups and followed for six months post-surgery to assess bone regeneration, surgical outcomes, and potential complications.

Who can participate

Age range18 Years – 55 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria * Patients aged 18-55 years. * Both males and females. * Patients with horizontal bone deficiency in the anterior maxillary region (\< 3 mm width) requiring augmentation prior to implant placement. * Adequate oral hygiene and commitment to follow-up visits. Exclusion Criteria: * Patients with systemic diseases affecting bone healing (e.g., uncontrolled diabetes, osteoporosis). * Heavy smokers (\>10 cigarettes/day). * Pregnant or lactating women. * Previous bone grafting procedures at the same site. * Patients on medications affecting bone metabolism (e.g., bisphosphonates).

What they're measuring

Anterior Horizontal Maxillary Alveolar ridge bone gain

Timeframe: Baseline (immediately post-surgery) 6 months after augmentation

Trial details

NCT IDNCT07210385

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-01-28