Not Yet RecruitingPhase 3

Randomized Controlled Trial of Different Antibiotic Duration Prior to Prostate Enucleation Surgery

250 participantsStarted 2026-01-01

Plain-language summary

To compare the risk of infectious complications (UTI, pyelonephritis, sepsis, hospital admission, ED visits) for patients with an indwelling urinary catheter (urethral or suprapubic) or CIC receiving 3 or 7 days of peri-operative antibiotic prophylaxis at time of Holmium Laser Enucleation of the Prostate

Who can participate

Age range18 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 1\. Candidate for HoLEP surgery 2. Must be 18 years or older. 3. The patient must be able to understand and willing to provide informed consent as described in this study protocol. Exclusion Criteria: * 1\. Under the age of 18 2. Refuse to provide informed consent 3. Anticipated need for perineal urethrostomy 4. History of multi-drug resistant organism on urine culture that is not susceptible to any oral agents

What they're measuring

Infectious complications

Timeframe: 0-90 days postoperatively

Trial details

NCT IDNCT07209150

SponsorOhio State University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-12-30

Contact for this trial

Matthew Lee, MD

614-293-8155 matthew.lee@osumc.edu

View on ClinicalTrials.gov More BPH With Urinary Obstruction trials