CompletedNot Applicable

Metal Artifact Reduction Sequence MRI for Surgical Decision-Making in Infected Unicompartmental Knee Arthroplasty

China28 participantsStarted 2017-06-01

Plain-language summary

A single-center retrospective cohort study was conducted in the Department of Orthopedics of Fujian Medical University Affiliated First Hospital. This study reviewed 28 patients who received unicompartmental prosthetic joint infection (uPJI) treatment at this institution from 2017 to 2023. The personal information of the patients, including age, gender, affected side, age-adjusted Charles Syndrome Index (aCCI), inflammation markers, lesion range on magnetic resonance angiography (MARS-MRI), lesion range observed directly during surgery and surgical methods, were recorded in detail. The study evaluated the clinical decision-making of a standardized MARS-MRI-guided treatment protocol for uPJI by reviewing the clinical outcomes of uPJI patients in a single PJI center.

Who can participate

Age range18 Years – 90 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Diagnosis of uPJI on the basis of medical history, symptoms, imaging data, etc.;
✓. Treatment by internal fixation surgery;
✓. Normal cognitive function;
✓. Informed consent obtained from the patient or family.

Exclusion criteria

✕. Significant missing data: In accordance with the Transparent Reporting of a Multivariate Prediction Model for Individual Prognosis or Diagnosis (TRIPOD) statement, only cases with complete key variables (missing rate \<5%) were included;
✕. Severe preoperative systemic comorbidities (e.g., decompensated liver/renal failure, active pneumonia, malignancy, and cachexia) and/or a history of mental illness;
✕. Missing postoperative follow-up.

What they're measuring

Infection control or not according to the MSIS criteria

Timeframe: preoperative and two-year follow-up

The Hospital for Special Surgery Knee Score (HSS) score

Timeframe: preoperative and two-year follow-up

Trial details

NCT IDNCT07208968

SponsorFirst Affiliated Hospital of Fujian Medical University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-06-30

View on ClinicalTrials.gov More Prosthetic Joint Infection trials