By InvitationNot Applicable

Effect of Theta-burst rTMS Therapy on the Clinical and Cognitive Symptoms of Patients With Therapy Resistant Depression and Response Prediction With Neuroimaging Methods.

Hungary54 participantsStarted 2025-06-13

Plain-language summary

The primary aim of the study is to find the combination of neuroimaging-related markers, demographics, and clinical characteristics that predict the response of patients with therapy-resistant depression to theta-burst rTMS treatment. The secondary aim is to monitor the cognitive effects of TMS therapy.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. diagnosis of depression
✓. 18 years of age
✓. Beck depression inventory score above 12 (screening)
✓. MADRS score above 6 (baseline)

Exclusion criteria

✕. serious cognitive impairment
✕. mental retardation
✕. history of head injury with loss of consciousness for more than 1 hour
✕. alcohol or drug abuse within the past 3 months

What they're measuring

Clinical symptoms

Timeframe: 120 days

Trial details

NCT IDNCT07207239

SponsorSemmelweis University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-06-13

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