Active — Not RecruitingPhase 4

Microderm for Root Coverage Procedures

United States20 participantsStarted 2025-02-13

Plain-language summary

This randomized pilot study will compare Acellular Dermal Matrix (ADM) and a microsurfaced Acellular Dermal Matrix (mADM) for wound healing, root coverage, gum tissue coverage of the surgical site, blood flow to the site, and patient comfort.

Who can participate

Age range18 Years

SexALL

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Exclusion criteria

✕. Current smokers or users of nicotine replacement products
✕. Patients with diabetes (HbA1c \> 5.6%)
✕. Pregnant or lactating women
✕. Surgical sites with previous soft tissue graft.
✕. Patients with a history of bisphosphonate therapy, radiotherapy in the head and neck region for malignancies, or chemotherapy for treatment of malignant tumors
✕. Patients who are taking anticoagulant and antiplatelet medications.
✕. Patients with contraindications, e.g., allergy, for any of the medications used in the study (benzocaine, lidocaine, chlorhexidine rinse, ibuprofen)
✕. Poor oral hygiene (PII \>2)

What they're measuring

Clinical root coverage in percentage

Timeframe: From enrollment to up to one year after connective tissue graft surgery.

Trial details

NCT IDNCT07203326

SponsorOhio State University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-08-31

View on ClinicalTrials.gov More Connective Tissue Graft trials