CompletedNot Applicable

Effects of Oxaliplatin-Induced Peripheral Neuropathy on Hand Function, Grip Strength and Quality of Life in Colorectal Cancer Patients

Turkey (Türkiye)103 participantsStarted 2025-04-24

Plain-language summary

The aim of this study is to investigate the effects of oxaliplatin-induced peripheral neuropathy on hand function, grip strength, and quality of life in colorectal cancer patients. Assessing the motor symptoms of CIPN and sharing the results in clinical settings will help guide evidence-based practices and interventions.

Who can participate

Age range

20 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Receiving chemotherapy due to a diagnosis of locally advanced or metastatic colorectal cancer, * Having received at least 3 cycles of single or combined oxaliplatin-based chemotherapy, * Aged 20 years or older, * No speech or hearing impairments, * Voluntary participation in the study. Exclusion Criteria: * Development of peripheral neuropathy due to causes other than chemotherapy (e.g., tumor compression, nutritional disorders, infections, or major systemic diseases such as diabetes mellitus), * Presence of mental or cooperation problems.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Hand Grip Strength Assessment

Timeframe: baseline only

Finger Grip Strengths (Tip, Key, and Palmar Grip)

Timeframe: baseline only

Hand Function Assessment (Duruöz Hand Index)

Timeframe: baseline

Hand Function Assessment (Michigan Hand Outcomes Questionnaire)

Timeframe: baseline

Fine Motor Skill Assessment (Minnesota Manual Dexterity Test)

Timeframe: baseline

Nine-Hole Peg Test (NHPT)

Timeframe: Baseline

Trial details

NCT IDNCT07203066

SponsorFenerbahce University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-01-20

View on ClinicalTrials.gov More Peripheral Neuropathy Due to Chemotherapy trials

Plain-language summary

Who can participate

Age range

20 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Hand Grip Strength Assessment

Timeframe: baseline only

Finger Grip Strengths (Tip, Key, and Palmar Grip)

Timeframe: baseline only

Hand Function Assessment (Duruöz Hand Index)

Timeframe: baseline

Hand Function Assessment (Michigan Hand Outcomes Questionnaire)

Timeframe: baseline

Fine Motor Skill Assessment (Minnesota Manual Dexterity Test)

Timeframe: baseline

Nine-Hole Peg Test (NHPT)

Timeframe: Baseline