Not Yet RecruitingNot Applicable

Organ Dysfunction Changes in Acute Necrotizing Pancreatitis Patients With Sepsis Following Open Necrosectomy

China700 participantsStarted 2025-10-05

Plain-language summary

The purpose of this retrospective study was to characterize the changes in organ dysfunction among patients with acute necrotizing pancreatitis complicated by sepsis who underwent open necrosectomy.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Patients 18 years or older
✓. Diagnosis of Acute pancreatitis according to the revised Atlanta classification, requires two of thefollowing three criteria: (A) typical abdominal pain, (B) an increase in serum amylase or lipaselevels higher than three times the upper limit of normality, and (C) signs of AP in imaging3)Patients with confirmed or suspected infected pancreatic or peripancreatic necrosis werescheduled for open necrosectomy
✓. Meet Sepsis-3 criteria

What they're measuring

Measure organ dysfunction change after open necrosectomy with respect to time

Timeframe: up to postoperative day 7, or at hospital discharge, whichever comes first

Trial details

NCT IDNCT07201246

SponsorWest China Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-12-30

Contact for this trial

Chunling Jiang, PhD

02885423593 jiangchunling@scu.edu.cn

View on ClinicalTrials.gov More Necrotizing Pancreatitis trials