RecruitingNot Applicable

Randomized, Double-blind Crossover Trial Comparing Low-GI Functional vs. Standard Wholegrain Carbohydrates on Glycolipid Metabolism and Vascular Stress Markers in Adults With Suboptimal Triglyceridemia

Italy40 participantsStarted 2026-02-02

Plain-language summary

Low-glycemic index (GI) carbohydrates help prevent type 2 diabetes and cardiovascular disease by reducing postprandial glucose, insulin spikes, inflammation, and triglyceride synthesis. They improve weight, lipid profiles, and vascular health. Our study will compare functional low-GI vs. standard wholegrain carbs in a Mediterranean diet to assess their effect on the Triglycerides-Glucose Index, a marker of metabolic and cardiovascular risk, in subjects with suboptimal triglyceride levels.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Male or female aged ≥ 18 years * TG\>150 mg/dL * Subjects who have the capability to communicate and to comply with the study's requirements. * Subjects agree to participate in the study and having dated and signed the informed consent form. Exclusion Criteria: * Gluten hypersensitivity/Coeliac disease diagnosis * BMI\>30 kg/m2 * Any preventive treatments (i.e. lipid-lowering drugs, antihypertensives) not stabilized in type and dose for at least 3 months * Any medical or surgical condition that would limit the patient adhesion to the study protocol.

What they're measuring

Impact of Low-GI Functional Carbohydrates on TyG Index

Timeframe: 28 days

Trial details

NCT IDNCT07198789

SponsorUniversity of Bologna

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-09-29

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