CompletedNot Applicable

Different Hold Durations in Isometric Exercises

Egypt127 participantsStarted 2026-01-30

Plain-language summary

this stuy tries to evaulate the best contraction (hold time) during isometric effort that can provide the best therapeutic effects on muscular performance in patients with knee osteoarthritis

Who can participate

Age range

40 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * prediagnosed case of knee OA as per the American College of Rheumatology (ACR) and radiological evidence of primary osteoarthritis of grade 3 or less on the Kellgren Lawrence scale; * age between 40-65 years, including both men and women. * unilateral or bilateral involvement (in the case of bilateral involvement, the more symptomatic knee was included). Exclusion Criteria: * Other knee joint pathologies, eg, Chondromalacia patella, plica syndrome, * Neurological disorders. * Patients having lower extremity injury/surgeries in the past 6 months, * Hip or knee fractures or deformity, * joint infections and inflammatory joint disease, * physical therapy on the knee within the last 3 months or steroid injections,

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

pain by numeric pain rating scale

Timeframe: at baseline and after 1month of trreatment

Function using Western Ontario and McMaster Universities Osteoarthritis

Timeframe: will be assessed at baseline and after 1 month of treatement

function using Five Times Sit to Stand Test

Timeframe: at baseline and after 1month of treatment

muscle strength using the one-repetition maximum (1RM) test for knee extension

Timeframe: at baseline and after 1 month of treatement

Trial details

NCT IDNCT07198204

SponsorUniversity of Hail

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-01-30

View on ClinicalTrials.gov More Knee Arthritis Osteoarthritis trials