Healing After Endodontic Microsurgery Using a Rotary Bur Versus Piezoelectric Unit for Osteotomy … (NCT07197658) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Healing After Endodontic Microsurgery Using a Rotary Bur Versus Piezoelectric Unit for Osteotomy and Root Resection
Greece124 participantsStarted 2023-04-25
Plain-language summary
The goal of this clinical trial is to compare bone healing after using apical tooth microsurgery to remove root end infection, either by use of rotary burs for cutting bone and root end, or by use of piezoelectric surgery for the same procedures.
The main questions it aims to answer are:
* Is there a difference in bone healing and reformation between the two surgical procedures ?
* Is there a difference in bone healing between cutting the bone with a rotary bur and cutting the bone with the 'bone window' technique that uses piezoelectric unit ?
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18 years and older consenting to the surgical procedure as well as agreeing to preoperative, postoperative and at least one follow-up CBCT evaluation after 12 months
* Noncontributory medical history (American Society of Anesthesiologists class I and II)
* A history of previous endodontic treatment with radiographic presence of apical periodontitis
* A true endodontic lesion: microsurgical classification A, B, or C according to Kim and Kratchman, 2006.
* Lesion size 10 mm or smaller in diameter measured on preoperative CBCT
* Coronal restoration should be present at the time of follow up examination.
Exclusion Criteria:
* Nonconsenting patients and patients younger than 18 years of age
* Medical history with American Society of Anesthesiologists class III to V
* Insufficient coronal restoration
* Nonrestorability or traumatized teeth
* Teeth with microsurgical classification D, E, or F according to Kim and Kratchman, 2006.
* Mobility I or higher
* Radiographic presence of nonapical root resorption
* Teeth with a vertical root fracture or coronal/ midroot perforation
* Lesion size larger than 10 mm in diameter measured on preoperative CBCT
* Use of bone graft material for regeneration
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Two dimensional radiographic bone healing
Timeframe: From execution of the microsurgical procedure to one year or later follow up examination
2
Three dimensional radiographic bone healing
Timeframe: From execution of the microsurgical procedure to one year or later follow up examination
Trial details
NCT IDNCT07197658
SponsorNational and Kapodistrian University of Athens