Efficacy of Universal Bonding Agents as Desensitizers (NCT07197437) | Clinical Trial Compass
CompletedNot Applicable
Efficacy of Universal Bonding Agents as Desensitizers
China14 participantsStarted 2023-02-27
Plain-language summary
The goal of this clinical trial is to learn if the adhesive Single Bond Universal works to treat dentin hypersensitivity in adults. It will also learn about the durability of Single Bond Universal. The main questions it aims to answer are:
Does Single Bond Universal has the function to treat dentin hypersensitivity in adults? Researchers will compare Single Bond Universal to a traditional desensitizer Hybrid Coat to see which one has higher efficiency and longer durability.
Participants will:
Receive the treatment of Single Bond Universal or Hybrid Coat at the first visit.
Visit the clinic at 1, 3, 6, 9, 12 months for follow-up evaluation. Reassess dentin sensitivity at each visit and record in terms of VAS score.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Participants aged ≥ 18 years who were able to provide written informed consent.
. Participants confirmed as healthy according to the examiner, without clinically significant diseases that could interfere with study outcomes.
. Participants with symptoms of dentin hypersensitivity affecting symmetrical teeth on both sides due to gingival recession.
. Symptomatic teeth without caries, filling materials, or use as abutments for removable partial dentures.
Exclusion criteria
. Individuals with dentin hypersensitivity caused by other factors (e.g., erosion or wedge-shaped defects).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
treatment efficacy of the tooth: the change in VAS score before and after desensitization
Timeframe: from enrollment to the last follow-up (12 months after treatment)
. Individuals with teeth exhibiting deep periodontal pockets (≥ 4 mm) or with a difference in gingival recession between the two symptomatic teeth of ≥ 1 mm.
. Individuals who had received treatment or used toothpaste for dentin hypersensitivity within the previous 4 weeks.
. Individuals who had undergone tooth bleaching or periodontal treatment within the previous 4 weeks.
. Individuals who had undergone cervical restorative treatment. Individuals who had taken nonsteroidal anti-inflammatory drugs or narcotic analgesics within the previous week.