RecruitingNot Applicable

Feasibility Trial of Combination of Obstetrical Carrier Screening and Hereditary Cancer Screening

United States1,000 participantsStarted 2026-02-12

Plain-language summary

The investigators hypothesize that preconception and pregnancy may be a feasible and effective time to offer inherited cancer risk screening. This study will assess interest in cancer genetic testing among patients receiving routine prenatal care or preconception care. The goal is to evaluate the acceptability of hereditary cancer testing when offered alongside standard prenatal genetic screening. The study will also explore whether universal screening in this population could support early cancer prevention

Who can participate

Age range18 Years – 55 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria: * Age: 18 years - 55 years * Patients receiving obstetrical-related care at a CUMC-affiliated enrollment site * Patients who have elected to undergo OCS with the CUMC-affiliated obstetrics provider * Patients with prior OCS but planned to repeat OCS are eligible * Patients can speak and read in English or Spanish Exclusion criteria: * Patients who have previously completed a multigene hereditary cancer syndrome panel * Patients that have a hematologic cancer or hematologic pre-cancer * Patients who have a history of an autologous bone marrow transplant

What they're measuring

Percentage of Participants Who Complete Both HCS and OCS

Timeframe: Approximately at the end of recruitment, expected at 2 years

Trial details

NCT IDNCT07195071

SponsorColumbia University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-12-31

Contact for this trial

Jessica Giordano

212-305-7250 jlg2197@cumc.columbia.edu

View on ClinicalTrials.gov More Hereditary Cancer Syndrome trials