RecruitingNot Applicable

Clinical and Biological Signs of Dapagliflozin Overdose in ICU Patients With Metformin Poisoning

France50 participantsStarted 2025-04-11

Plain-language summary

This study looks at patients admitted to intensive care for drug poisoning involving metformin, a common diabetes medication. Researchers will compare two groups: patients who overdosed on metformin alone and those who took both metformin and dapagliflozin, another diabetes drug. The goal is to find clinical or laboratory signs that could help doctors quickly recognize a dapagliflozin overdose in this context, which could improve treatment and patient outcomes.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults aged 18 years or older * Admission to an intensive care unit (ICU) due to acute drug poisoning * Documented exposure to either: * Metformin alone * Metformin in combination with dapagliflozin Exclusion Criteria: * Patients under 18 years of age * No exposure to metformin * Exposure to dapagliflozin without metformin

What they're measuring

Identification of clinical and biological differences between patients admitted to intensive care for metformin overdose alone versus those with combined metformin and dapagliflozin overdose.

Timeframe: 10 years

Trial details

NCT IDNCT07193069

SponsorCentre Hospitalier de Saint-Denis

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-04-11

View on ClinicalTrials.gov More Drug Overdose trials