CompletedNot Applicable

Effect of BIS-Guided Anesthesia on Postoperative Nausea and Vomiting in Pediatric Patients

Turkey (Türkiye)58 participantsStarted 2025-09-24

Plain-language summary

This randomized controlled trial will evaluate the effect of bispectral index (BIS)-guided anesthesia on postoperative nausea and vomiting (PONV) in children aged 3-8 years undergoing elective adenoidectomy. Fifty-eight patients will be randomized to BIS-guided anesthesia (target 40-60) or standard clinical management. The primary outcome is PONV incidence within 24 hours. Secondary outcomes include antiemetic use, emergence time, hospital stay, and parental satisfaction.

Who can participate

Age range3 Years – 8 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Children aged 3-8 years * ASA physical status class I-II * Scheduled for elective adenoidectomy * Written informed consent obtained from parents Exclusion Criteria: * Children with a previous history of PONV * Patients receiving antiemetic, steroid, or sedative medication * Acute upper respiratory tract infection * History of neurological or psychiatric disorders * Body mass index (BMI) below the 5th percentile or above the 95th percentile * Anatomical airway abnormalities

What they're measuring

Incidence of postoperative nausea and vomiting (PONV) during the first 24 hours postoperatively.

Timeframe: T1: Immediately before extubation T2: 6 hours after extubation T3: 12 hours after extubation T4: 24 hours after extubation

Trial details

NCT IDNCT07189845

SponsorEngin Çetin

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2026-01-20

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