Not Yet RecruitingNot Applicable

SWE to Detect Enthesitis in PsA: Relationship With SIRT2 Expression and Disease Activity

Egypt57 participantsStarted 2025-10

Plain-language summary

1. To assess the diagnostic utility of shear-wave elastography (SWE), gray-scale (GS) ultrasound, and Power Doppler (PD) in detecting Patellar and Achilles tendinopathy in psoriatic patients with and without arthritis. 2. Investigate the relation between SWE, GS ultrasound, and PD finding and SIRT2 expression levels. 3. Evaluate the association of the imaging findings and SIRT2 levels with psoriatic arthritis disease activity score.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * Patients diagnosed as PsO by a dermatologist according to PASI score. * Patients diagnosed as PsA by rheumatologist according to CASPAR classification criteria for psoriatic arthritis * Adult patients of both sexes with an average \> 18 years Exclusion Criteria: * Patients with a history of metabolic disease affecting tendons. * Patients with history of surgery, injury or trauma of patellar and/or Achilles tendon. * Patients with other rheumatological diseases. * Patients below 18.

What they're measuring

Assessment and comparting the diagnostic utility of shear-wave elastography (SWE) , Gray-scale (GS) ultrasound. and Power Doppler (PD) in detecting tendinopathy in psoriatic patients with and without arthritis.

Timeframe: At baseline (single study visit)

Trial details

NCT IDNCT07188688

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-10

Contact for this trial

Nada MMN ELSHENAWY, Specialist

+201002973457 nadaaa.mahmoud@med.aun.edu.eg

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