SWE to Detect Enthesitis in PsA: Relationship With SIRT2 Expression and Disease Activity (NCT07188688) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
SWE to Detect Enthesitis in PsA: Relationship With SIRT2 Expression and Disease Activity
Egypt57 participantsStarted 2025-10
Plain-language summary
1. To assess the diagnostic utility of shear-wave elastography (SWE), gray-scale (GS) ultrasound, and Power Doppler (PD) in detecting Patellar and Achilles tendinopathy in psoriatic patients with and without arthritis.
2. Investigate the relation between SWE, GS ultrasound, and PD finding and SIRT2 expression levels.
3. Evaluate the association of the imaging findings and SIRT2 levels with psoriatic arthritis disease activity score.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients diagnosed as PsO by a dermatologist according to PASI score.
* Patients diagnosed as PsA by rheumatologist according to CASPAR classification criteria for psoriatic arthritis
* Adult patients of both sexes with an average \> 18 years
Exclusion Criteria:
* Patients with a history of metabolic disease affecting tendons.
* Patients with history of surgery, injury or trauma of patellar and/or Achilles tendon.
* Patients with other rheumatological diseases.
* Patients below 18.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Assessment and comparting the diagnostic utility of shear-wave elastography (SWE) , Gray-scale (GS) ultrasound. and Power Doppler (PD) in detecting tendinopathy in psoriatic patients with and without arthritis.