RecruitingNot Applicable

A Study Looking at a New Nerve Surgery to Help Men Regain Erections After Prostate Cancer Surgery

Canada100 participantsStarted 2026-01-30

Plain-language summary

A single arm prospective pilot trial evaluating the 1-year erectile recovery outcomes and the safety of patients undergoing a somatic to autonomic nerve grafting procedure for restoration of erectile function in patients who have lost erectile function following radical prostatectomy for prostate cancer. During this study a total of 100 patients who have persistent erectile dysfunction for more than 18 months post prostatectomy will undergo a post radical prostatectomy nerve restoration procedure (PRP-NR).

Who can participate

Age range18 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Severe ED (IIEF score 5-7) and more than 12 months from prostatectomy OR
✓. Moderate ED (IIEF score 8-11) and more than 18 months from prostatectomy

What they're measuring

International Index of Erectile Function-5 (IIEF-5)

Timeframe: 4 weeks post PRP-NR

International Index of Erectile Function-5 (IIEF-5)

Timeframe: 3 months post PRP-NR

Clinical Evolution of Erectile Function (CEEF)

Timeframe: 24 months post PRP-NR

Clinical Evolution of Erectile Function (CEEF)

Timeframe: 18 months post PRP-NR

Clinical Evolution of Erectile Function (CEEF)

Timeframe: 12 months post PRP-NR

Clinical Evolution of Erectile Function (CEEF)

Timeframe: 6 months post PRP-NR

Clinical Evolution of Erectile Function (CEEF)

Timeframe: 3 months post PRP-NR

Clinical Evolution of Erectile Function (CEEF)

Timeframe: 4 weeks post PRP-NR

Trial details

NCT IDNCT07188064

SponsorSir Mortimer B. Davis - Jewish General Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-11

Contact for this trial

Victor McPherson, MD

514-340-8222 victor.mcpherson@mcgill.ca

View on ClinicalTrials.gov More Prostate Cancer trials

Plain-language summary

Who can participate

Age range18 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Severe ED (IIEF score 5-7) and more than 12 months from prostatectomy OR
✓. Moderate ED (IIEF score 8-11) and more than 18 months from prostatectomy

What they're measuring

International Index of Erectile Function-5 (IIEF-5)

Timeframe: 4 weeks post PRP-NR

International Index of Erectile Function-5 (IIEF-5)

Timeframe: 3 months post PRP-NR

Clinical Evolution of Erectile Function (CEEF)

Timeframe: 24 months post PRP-NR

Clinical Evolution of Erectile Function (CEEF)

Timeframe: 18 months post PRP-NR

Clinical Evolution of Erectile Function (CEEF)

Timeframe: 12 months post PRP-NR

Clinical Evolution of Erectile Function (CEEF)

Timeframe: 6 months post PRP-NR

Clinical Evolution of Erectile Function (CEEF)

Timeframe: 3 months post PRP-NR

Clinical Evolution of Erectile Function (CEEF)

Timeframe: 4 weeks post PRP-NR