Not Yet RecruitingNot Applicable

Effect of Sodium Glucose Co-transporter 2 Inhibitors on Left Atrial Remodeling in Diabetic Patients

100 participantsStarted 2025-10-01

Plain-language summary

To evaluate and follow-up left atrial volume, diastolic function by 2D echocardiography and left atrial strain parameters using speckle-tracking echocardiography in patients with type 2 diabetes mellitus (T2DM) before and after treatment with SGLT2 inhibitors

Who can participate

Age range40 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosed T2DM on antidiabetic medication not including SGLT2 inhibitors. * HbA1c ≤ 7%. * Age 40-75 years. * Sinus rhythm. * Informed consent obtained Exclusion Criteria: * History of atrial fibrillation or flutter. * Patients treated with SGLT2 inhibitors. * Severe mitral valve regurgitation or stenosis. * Previous myocardial infarction. * Previous percutaneous coronary intervention(PCI) or coronary artery bypass grafting (CABG). * LV Ejection fraction \<50% . * Severe renal impairment (eGFR \< 30 mL/min/1.73 m²) * Uncontrolled hypertension (BP \> 160/100 mmHg) * Inadequate echocardiographic windows or incomplete data

What they're measuring

follow-up and evaluation of LA remodeling in patients with type-2 diabetes mellitus ( T2DM) before and after treatment with SGLT2 inhibitors

Timeframe: 6 months follow-up

Trial details

NCT IDNCT07186153

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-10-01

Contact for this trial

Abanoub Fayoumy Shawky, Bachelor

+201207937601 abanoubfayoumy97@gmail.com

View on ClinicalTrials.gov More SGLT 2 Inhibitors trials