CompletedNot Applicable

Clinical Efficacy of NST With Adjunctive Local Delivery of Ozonated Olive Versus Curcumin Gel in Stage II Grade B Periodontitis.

Egypt40 participantsStarted 2025-11-02

Plain-language summary

The aim of this clinical trial is to evaluate the effectiveness of local delivery ozonated olive gel versus curcumin gel as adjunct to scaling and root planing in the treatment of stage II grade B periodontitis in on both males and females in the age group between 18 and 50 years. outcome measures are Clinical attachment level (CAL), plaque index (PI), gingival index (GI).

Who can participate

Age range18 Years – 50 Years

SexALL

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Inclusion criteria

✓. Patients diagnosed with stage II periodontitis defined by having interdental CAL 3-4 mm and presence of pocket depth (PD) ≤ 5 mm, and grade B periodontitis characterized by a moderate rate of disease progression.
✓. Patients agree to a 3-month follow-up period and provide an informed consent.

Exclusion criteria

✕. Presence of prosthetic crowns, overhanging restorations and orthodontic treatment.
✕. Teeth with both endo-perio lesions.
✕. Antibiotics therapy that has an impact on the clinical signs and symptoms of periodontitis in the previous 3 months.
✕. Anti-inflammatory drugs in the previous 1 month.

What they're measuring

Clinical attachment level

Timeframe: 3 months

Trial details

NCT IDNCT07184268

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-03-15

View on ClinicalTrials.gov More Periodontitis, Adult trials