Not Yet RecruitingPhase 1/2

Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery.

60 participantsStarted 2026-01-01

Plain-language summary

This study aims to compare intranasal dexmedetomidine versus intranasal ketamine as a premedication in children undergoing surgery in our population. Hypothesis is Intranal dexmedetomidine is better than intranasal ketamine in producing preoperative sedation in pediatric patients undergoing surgery under general anesthesia.

Who can participate

Age range2 Years – 6 Years

SexALL

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Inclusion Criteria: * American society of Anesthesiologist (ASA) class-I and II * Children 2-6 years of age undergoing elective surgery Exclusion Criteria: * Known hypersensitivity to study drugs * Refusal of consent * Known renal, hepatic or cardiac dysfunction * Nasal deformity or pathology * Recent upper respiratory infection (within 2 weeks) * Children undergoing neurosurgery or ophthalmic surgery

What they're measuring

Sedation score as assessed by MOAA/S

Timeframe: 6 months

Trial details

NCT IDNCT07180095

SponsorLiaquat National Hospital & Medical College

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-06-30

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