CompletedNot Applicable

Pre- and Post-TAVI Patient Assessment: Advancing Outcome Precision in Aortic Valve Therapy

Egypt, Saudi Arabia100 participantsStarted 2025-02-01

Plain-language summary

The aim of this study is to evaluate the combined utility of the left atrial coupling index (LACI) and left ventricular speckle tracking echocardiography (LVSTE) in improving risk stratification and outcome prediction for patients undergoing Transcatheter Aortic Valve Implantation (TAVI). This study seeks to identify novel prognostic markers that enhance the prediction of mortality, heart failure, and functional recovery, ultimately enabling more personalized clinical decision-making and optimized patient outcomes by integrating the advanced echocardiographic parameters into pre-procedural assessments,.

Who can participate

Age range50 Years – 102 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients diagnosed with severe aortic stenosis and scheduled for TAVI. Exclusion Criteria: * Patients with significant mitral or tricuspid valve disease requiring intervention. * History of atrial fibrillation or other arrhythmias that preclude accurate LACI measurement. * Poor echocardiographic window preventing reliable imaging.

What they're measuring

Repeated hospitalization in one year

Timeframe: one year

Need for permanent pacemaker

Timeframe: 6 months

Myocardial infarction within one year

Timeframe: one year

Stroke in one year

Timeframe: one year

Trial details

NCT IDNCT07179302

SponsorDamanhour University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-10-30

View on ClinicalTrials.gov More Aortic Valve Stenosis trials