Active — Not RecruitingNot Applicable

Peripheral Artery Disease in Regular Hemodialysis Patients

Egypt120 participantsStarted 2025-07-13

Plain-language summary

Recent studies have reinforced the association between high NLR and PAD in hemodialysis patients. This highlights the need for further studies to confirm its predictive value and determine optimal cut-off thresholds tailored to local patient populations. Accordingly, the present study aims to investigate the relationship between NLR and the presence of PAD in patients undergoing regular hemodialysis. By establishing this association in a well-defined population, we hope to provide evidence that supports the use of NLR as a simple, cost-effective tool for PAD risk stratification and early intervention

Who can participate

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult patients aged ≥18 years. * Undergoing maintenance hemodialysis for at least 3 months (thrice weekly) * Able to provide informed consent. * Willing to undergo clinical and laboratory evaluations, including peripheral vascular assesment Exclusion Criteria: * Active infection or sepsis at the time of evaluation .\* Patients who have a sedimentation rate of more than 60 mm/hour \*. Known autoimmune or hematologic disorders that may influence leukocyte count. * Current use of immunosuppressive therapy, corticosteroids, or chemotherapy.5. History of malignancy.6. Patients with incomplete medical records or unable to undergo peripheral vascular assessment.

What they're measuring

The aim of this study is to evaluate the predictive value of the neutrophil-to- lymphocyte ratio (NLR) for the presence of peripheral artery disease (PAD) in patients undergoing regular hemodialysis.

Timeframe: 6months

% of patients with affection in neutrophills to lymphocytes ratio in parient on regular hemodialysis.

Timeframe: 6 months

Trial details

NCT IDNCT07179211

SponsorSohag University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-01-13

View on ClinicalTrials.gov More Chronic Kidney Disease trials