Human Skeletal Muscle Response to 5 Days of Bedrest in Young Adults

Inclusion Criteria: * Males and females 18-30 years * BMI between 18.5-28 kg/m2 * Weight stable (within ±2kg for 6 months) * Generally healthy as assessed by medical and physical activity questionnaires * recreationally active Exclusion Criteria: * a BMI \< 18.5 and \> 28 kg/m2 * the use of insulin to control blood glucose levels * a history of any cardiovascular, respiratory, metabolic diseases, neuromuscular or bone-wasting diseases * the use of any medication that may affect muscle protein turnover (e.g. androgen or anabolic hormone therapy, chemotherapy) * a (family) history of thrombosis, platelet or coagulation disorders, or antiplatelet therapy and the use of anticoagulant medications * the presence of any unremoved, or partially removed metals underneath the skin * a history of head or eye injury involving metal fragments * have some type of implanted electrical device (such as a cardiac pacemaker or neurostimulator) * have implanted metal objects as a result of surgery, such as artificial joints, aneurysm clips, metal staples * are, or may be, pregnant * are wearing metal braces on their teeth.