Not Yet RecruitingNot Applicable

Preoperative vs Postoperative Revascularization in Coronary Heart Disease Patients Undergoing Time-Sensitive Non-Cardiac Surgery (CHRONOS-PCI)

China140 participantsStarted 2025-10

Plain-language summary

To compare the safety and efficacy of preoperative versus postoperative revascularization strategies in patients with coronary heart disease undergoing time-sensitive non-cardiac surgery.

Who can participate

Age range18 Years – 80 Years

SexALL

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Inclusion criteria

✓. Moderate or severe stenosis of the left main coronary artery
✓. Multivessel disease involving the ostium of the left anterior descending artery
✓. Three-vessel disease with ≥70% stenosis in each major epicardial vessel

Exclusion criteria

✕. Karnofsky performance score \<60
✕. Eastern Cooperative Oncology Group (ECOG) performance status \>2

What they're measuring

Major Adverse Cardiovascular Events (MACE)

Timeframe: 180 days after the first invasive procedure (non-cardiac surgery or PCI)

Trial details

NCT IDNCT07175870

SponsorFirst Affiliated Hospital of Wenzhou Medical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2029-08

Contact for this trial

Hao Zhou

+86 13968801939 wyzh66@126.com

View on ClinicalTrials.gov More Coronary Artery Disease trials