CompletedNot Applicable

Chromosomal Translocations in Chandigarh Police

India203 participantsStarted 2021-11-01

Plain-language summary

The goal of this Non-Randomized Control Trial is to evaluate the prevalence of chromosomal translocations in occupationally stressed subjects and the molecular impact of yoga on such translocations and DNA damage response and repair in security guards of Chandigarh Police. The main questions it aims to answer are: Does yoga has any role in alleviating chromosomal translocations in healthy but occupationally stressed subjects? Does practice of yoga has any impact on molecular markers related to DNA damage response and repair before and after Yoga intervention in highly stressed individuals? Researchers will compare Control Group and Yoga group before and after Yoga intervention. Participants will be divided into two groups Control Group and Yoga Group. Yoga Group will be given yoga intervention for 3 months, 5 days a week and for 65 minutes in a day. Control Group will follow their daily routine without following the intervention. Before and after the intervention, blood samples will be collected from the participants of both groups and analysed for chromosomal translocations and DDRR markers.

Who can participate

Age range

25 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Individuals scoring more than 15 points on Cohen's scale. Once these subjects' consent to enrol, each one of them will be coded to maintain anonymity. Exclusion Criteria: * Individuals with complications in co-morbid conditions like Diabetes, Cirrhosis, etc. * Individuals of age less than 25 or more than 60 years. * Individuals who do not consent to be a part of this study. * Individuals who fail to comply with the yoga protocol in Intervention Group.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Prevalence of t(14;18) translocations using Nested PCR method

Timeframe: 3 months

Trial details

NCT IDNCT07174804

SponsorPost Graduate Institute of Medical Education and Research, Chandigarh

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-02-28

View on ClinicalTrials.gov More Chromosomal Translocations trials