The goal of this clinical trial is to evaluate whether genicular nerve block (GNB) is effective in reducing pain in patients with knee osteoarthritis. It will also assess the comparative efficacy of different injection protocols. The main questions it aims to answer are: Does genicular nerve block with corticosteroid and local anesthetic provide superior pain relief compared with local anesthetic alone or placebo? Are there differences in clinical outcomes between the three treatment groups? Researchers will compare three groups: GNB with corticosteroid plus local anesthetic GNB with local anesthetic alone Sham procedure with saline (placebo control) Participants will: Receive the assigned injection protocol in accordance with their group Be evaluated at baseline and scheduled follow-up visits for pain intensity and functional status Report their pain scores and functional limitations using standardized assessment tools
Age range
45 Years – 75 Years
Sex
ALL
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A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Pain intensity
Timeframe: at baseline, 1 week, and 1 month after treatment