Not Yet RecruitingNot Applicable

Congenital and Maternal Point of Care Rapid Testing for Syphilis Study, Uganda

Uganda24 participantsStarted 2025-09

Plain-language summary

Syphilis is an infection which affects about 1 in 25 pregnant women in Uganda. If the infection is not diagnosed and treated this can be a risk to the mother and unborn baby's health. This study aims to see whether a new test for syphilis infection in mothers and babies which can give a result in 10 minutes is as good as the standard tests that are done in the laboratory and take hours or days to provide results.

Who can participate

Age range14 Years

SexALL

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Inclusion Criteria: * Mothers delivering at Kawempe National Referral Hospital with a positive syphilis rapid diagnostic test during their current pregnancy. Exclusion Criteria: * Mothers who are unable to give written informed consent. * Mothers with evidence of neurological symptoms compatible with neurological syphilis. * Mothers who are aged less than 14 years. Emancipated and mature minors are allowed to consent for research per Ugandan law.11 * Mothers, who in the view of the study team, are unable to adhere to required study procedures

What they're measuring

Primary outcomes

Timeframe: At enrolment

Trial details

NCT IDNCT07173764

SponsorSt George's, University of London

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-12

View on ClinicalTrials.gov More Syphilis trials