RecruitingPhase 3

Efficacy and Safety Phase III Clinical Study of VC005 Tablets in Subjects With Active Ankylosing Spondylitis.

China420 participantsStarted 2025-12-26

Plain-language summary

This clinical trial is a multicenter, randomized, double-blind, controlled phase III clinical study.

Who can participate

Age range

18 Years – 70 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * The subject understands and voluntarily signs the informed consent form (ICF) and is willing and able to comply with the study protocol; * The subject is between 18 and 70 years of age (including borderline values) at the time of signing the ICF, regardless of gender; * The subject has been diagnosed with AS according to the 1984 New York Revised Criteria for Ankylosing Spondylitis Exclusion Criteria: * Those who may be allergic to VC005, similar drugs or their excipients. * Individuals who have undergone organ transplantation in the past and require continuous use of immunosuppressants. * Those who, for any reason, are considered by the investigator to be unsuitable for participation in this study.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Percentage of patients achieving an Assessment of disease activity (signs and symptoms) in ankylosing spondylitis 20% improvement (ASAS20) in response at week 12 of treatment.

Timeframe: week 12

Trial details

NCT IDNCT07172360

SponsorJiangsu vcare pharmaceutical technology co., LTD

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2027-08-30

Contact for this trial

xiaojuan lai

15358160458 lai_xiaojuan@vcarepharmatech.com

View on ClinicalTrials.gov More Active Ankylosing Spondylitis trials

Who can participate

Age range

18 Years – 70 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.