Segmentectomy vs Lobectomy for 2 - 3cm IASLC Grade 1-2 Lung Adenocarcinoma: A Multi-center RCT

Exclusion criteria

• ✕. Active bacterial or fungal infection (confirmed by imaging diagnosis or bacteriological examination with fever \>38°C).
• ✕. Multiple active cancers (synchronous or metachronous multiple primary cancers, excluding in situ carcinoma or intramucosal cancer lesions considered cured by local treatment; such lesions are not included in active multiple cancers).
• ✕. Patients with severe impairment of cardiac, hepatic, or renal function (cardiac function grade 3-4; ALT and/or AST more than 3 times the upper limit of normal; Cr exceeding the upper limit of normal).
• ✕. Patients with concomitant other malignant tumors or hematological diseases.
• ✕. Pregnant, planning to become pregnant, or lactating female patients (diagnosed with early pregnancy when urine HCG \>2500 IU/L).
• ✕. Any form of antitumor therapy before tumor resection, including interventional chemotherapy embolization, ablation, radiotherapy, chemotherapy, and molecular targeted therapy.
• ✕. Patients who participated in other tumor-related clinical trials within the past three months.
• ✕. Preoperative CT suggests ground-glass predominant nodules (CTR \< 0.5).