CompletedNot Applicable

Zinc Plus Saccharomyces Boulardii Versus Zinc Alone in the Treatment of Acute Diarrhea

Pakistan276 participantsStarted 2025-02-01

Plain-language summary

In literature combined therapy of zinc with S. boulardii in the treatment of acute diarrhea has not been addressed satisfactorily in the recent past. Therefore, this study was planned aiming to compare the mean time taken to resolve diarrhea and the mean time taken to resolve vomiting in children under 5 years of age having acute diarrhea with zinc plus S. boulardii versus zinc alone.

Who can participate

Age range1 Month – 5 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Children of either gender * Aged between 1 month up to 5 years * Presented with acute diarrhea Exclusion Criteria: * Children with concurrent acute illnesses (meningitis, sepsis, or pneumonia) * Severe chronic conditions (cystic fibrosis, endocrinopathies, food allergies, or chronic gastrointestinal diseases) * Severe undernutrition (weight-for-age \<60% of the 50th percentile of CDC 2000 standards) * Children who used probiotics, antibiotics, or anti-diarrheal drugs within the past 7 days * The presence of visible blood in stools

What they're measuring

Resolution of diarrhea

Timeframe: 7 days

Resolution of vomiting

Timeframe: 14 hours

Trial details

NCT IDNCT07168304

SponsorMuhammad Aamir Latif

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-07-31

View on ClinicalTrials.gov More Acute Watery Diarrhea trials