TerminatedPhase 2

Steroid Treatment for Elimination of Rebound Obstruction From Intranasal Decongestants

Stopped: low recruitment

United States3 participantsStarted 2025-11-10

Plain-language summary

This prospective, virtually administered trial conducted throughout the United States aims to evaluate a standardized protocol including the serial dilution of topical decongestants with concurrent topical steroids (triamcinolone), for elimination of dependence on topical decongestants.

Who can participate

Age range18 Years

SexALL

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Exclusion criteria

✕. Any history of sinonasal mass/tumor
✕. Any history of nasal polyps
✕. Septal perforation
✕. A diagnosis of one of the following conditions:
✕. eosinophilic granulomatosis with polyangiitis
✕. granulomatosis with polyangiitis
✕. Any current intranasal drug use such as cocaine.
✕. If they are currently using or have used intranasal steroid medications (oral or nasal) besides oxymetazoline for the past month.

What they're measuring

Responder rate

Timeframe: week 8

Trial details

NCT IDNCT07168148

SponsorWashington University School of Medicine

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-03-19

View on ClinicalTrials.gov More Nasal Obstruction trials