Neurological Complications and ICU Workload After Emergency Repair of Acute Type A Aortic Dissection (NCT07167628) | Clinical Trial Compass
CompletedNot Applicable
Neurological Complications and ICU Workload After Emergency Repair of Acute Type A Aortic Dissection
Taiwan274 participantsStarted 2021-01-01
Plain-language summary
Single-center retrospective cohort at China Medical University Hospital (Taichung, Taiwan) using fully de-identified electronic health records. Consecutive adults who underwent emergency repair of acute type A aortic dissection between 2021-01-01 and 2025-04-30 were pooled into one cohort. The study measures the incidence and patterns of early postoperative neurological complications and evaluates their association with intensive care unit (ICU) resource use, focusing on prolonged ICU length of stay (LOS ≥ 10 days), ICU and hospital LOS, and duration of mechanical ventilation (MV). No new data collection or patient contact occurs. Institutional Review Board (IRB) approval: CMUH114-REC1-139.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults (≥18 years) who underwent emergency repair of acute type A aortic dissection at China Medical University Hospital between 2021-01-01 and 2025-04-30.
Exclusion Criteria:
* Missing data in key variables required for analyses.
* Preoperative ischemic stroke within 30 days before surgery or preoperative modified Rankin Scale ≥4.
* Pregnancy.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study specifically tracked neurological complications like stroke, coma, paraplegia, and delirium after emergency surgery for acute Type A aortic dissection — based on what this research found, what does the data suggest about my personal risk for these complications given my current condition?
2The trial also measured prolonged ICU stays of 10 days or more — can you walk me through what factors the study identified that made patients more likely to need that extended ICU time, and how those factors apply to me?
3Since this was an observational study rather than a treatment trial, it was measuring outcomes rather than testing a new therapy — does the data from this research actually change how my surgical team would approach my care or manage my recovery in the ICU?
4The conditions studied here — acute kidney injury, delirium, and coma — can have serious long-term effects beyond the hospital stay — based on what this study found, what should I realistically expect for my recovery and quality of life in the months after surgery?
5Given that this trial has already completed and was focused on understanding complications rather than testing a new intervention, is there a different ongoing trial or a newer treatment approach that might be worth considering alongside standard emergency repair?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Prolonged ICU length of stay (LOS ≥10 days)
Timeframe: Through ICU discharge during the index admission (up to 30 days).
2
Any postoperative neurological complication
Timeframe: Through hospital discharge during the index admission (up to 30 days).