Background: Dietary modifications, like changing macronutrient distribution and improving food quality, are the main therapeutic approaches for managing oxidative stress, inflammation, and metabolic syndrome. Mediterranean diet is scientifically endorsed as promoting healthy aging and reducing the risk of cognitive decline when compared to the Western-style diet pattern. Objective: Analyzing the beneficial effect of the Mediterranean diet (MD) on anthropometric indices, inflammatory markers, lipid profiles in psychiatric patients with metabolic syndrome, compared to the standard hospital diet (HD). Methods: The study was designed as a crossover study; 15 male and 15 female participants with psychiatric disorders were enrolled, and they were intervened with either MD or HD for 8 weeks. Anthropometric parameters, inflammatory cytokines, lipid profile, and metabolic markers were measured with two stages of pre- and post-intervention.
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Change in Anthropometric measurement
Timeframe: Baseline, Week 8, 11 week, and Week 18
Blood pressure
Timeframe: Baseline, Week 8, week 11, and Week 18
Change in Fasting Blood Glucose
Timeframe: Baseline, Week 8, week 11 and Week 18
Change in Serum Lipid Profile
Timeframe: Baseline, Week 8, week 11 and Week 18