RecruitingNot Applicable

SBU-RESET: RElaxation, Stress Reduction and Epigenetics Trial in Cancer Survivors

United States100 participantsStarted 2025-09-17

Plain-language summary

Cancer survivors can experience health issues that cause chronic illness and lower quality of life. Yoga is a well-known holistic approach to health and overall well-being. Mindfulness has many benefits, including improved focus and less stress. This study aims to evaluate if yoga and/or mindfulness has a positive effect on cancer survivors social, emotional and physical well-being as well as their epigenetics. Epigenetics is how the environment can effect your genes; not by changing our DNA, but by turning genes on or off.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults over 18 years old * Primary diagnosis: Lung Cancer, Colon Cancer and Non-Hodgkin's lymphoma (NHL) * Six months post cancer-directed treatment (chemotherapy, targeted and immunotherapy). Patients with active disease (e.g. metastatic colorectal cancer) who are not receiving any cancer-directed treatment are eligible. * Able to provide a saliva sample * Gives informed consent and agrees to be randomly assigned * Able to complete the questionnaire(s) in English. Exclusion Criteria: * Adults with primary anal and/or primary rectal cancer. * Adult cancer survivors who are currently on an active treatment regimen. * Oral or any pathological conditions that can limit the ability to produce saliva. * Unable to participate in full length study period and follow up thereafter. * Is pregnant or plan to become pregnant during the study period. * Currently practicing yoga or SMART * Those on corticosteroid therapy. * Documented fall or syncope within the last 6 months

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Patient Reported Quality of Life (QOL) by EORTC QLQ-C30

Timeframe: 8 weeks

Patient Reported Quality of Life (QOL) by EORTC QLQ-SURV100

Timeframe: 8 weeks

Patient Reported Quality of Life (QOL) by QLQ-ANL27

Timeframe: 8 weeks

Patient Reported Quality of Life (QOL) by QLQ-BIL21

Timeframe: 8 weeks

Patient Reported Quality of Life (QOL) by QLQ-BN20

Timeframe: 8 weeks

Patient Reported Quality of Life (QOL) by QLQ-BR42

Timeframe: 8 weeks

Patient Reported Quality of Life (QOL) by QLQ-CLL17

Timeframe: 8 weeks

Patient Reported Quality of Life (QOL) by QLQ-CR29

Trial details

NCT IDNCT07161713

SponsorBarbara Nemesure

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-09-17

Contact for this trial

Stony Brook Cancer Center Clinical Trials

631-728-7425 CancerClinicalTrials@stonybrookmedicine.edu

View on ClinicalTrials.gov More Cancer Survivors trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Patient Reported Quality of Life (QOL) by EORTC QLQ-C30

Timeframe: 8 weeks

Patient Reported Quality of Life (QOL) by EORTC QLQ-SURV100

Timeframe: 8 weeks

Patient Reported Quality of Life (QOL) by QLQ-ANL27

Timeframe: 8 weeks

Patient Reported Quality of Life (QOL) by QLQ-BIL21

Timeframe: 8 weeks

Patient Reported Quality of Life (QOL) by QLQ-BN20

Timeframe: 8 weeks

Patient Reported Quality of Life (QOL) by QLQ-BR42

Timeframe: 8 weeks

Patient Reported Quality of Life (QOL) by QLQ-CLL17

Timeframe: 8 weeks

Patient Reported Quality of Life (QOL) by QLQ-CR29