CompletedNot Applicable

The Sponsor Assigns Test Products to Six Skin Areas According to a Concealed Randomization Schedule; Neither the Evaluating Physicians Nor the Participants Know Which Product is Applied to Which Site, Preventing Bias.

China30 participantsStarted 2024-12-21

Plain-language summary

This is a single-center, double-blind, randomized, and controlled study. The sponsor keeps the allocation of products to the six test sites confidential. Neither the evaluating physicians nor the participants know which product is applied to which site. The investigator will recruit 33 Chinese female participants and aim to complete the study with at least 30 of them. Each participant will be followed for 23 consecutive days. * \*\*Day 0\*\*: After signing informed consent and passing screening, a staff member performs a dansyl chloride patch test. The reagent is placed in a Finn chamber, applied to the inner forearm, and sealed with waterproof tape. * \*\*Day 1 (≥20 h later)\*\*: Participants return to the site. The patches are removed, photographs are taken, and the designated test products are applied to the marked areas. * \*\*Days 2-21\*\*: Participants visit daily for product application by staff. After each use they report any adverse reactions, specifying symptoms, severity, location, and duration. Starting on Day 1, a dermatologist performs daily clinical scoring and photography of the test areas. Throughout the study, participants must avoid sunscreen and any other skin-care products on the inner forearms. From Day 0 to Day 1 they may not bathe or wet the forearms; during the remaining application period they may shower but must not rub or scrub the inner forearms, and must still refrain from any other topical products.

Who can participate

Age range

18 Years – 65 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: \- 1) Chinese physically healthy female participants, aged between 18 and 65 years old; 2) All skin types (including dry, normal, oily, and combination); 3) Have no significant skin defects, scars, tattoos, protrusions, open wounds, or other factors that would affect the evaluation on the inner side of the forearm skin; 4) Have no severe allergic reactions to the testing reagents containing dansyl chloride; 5) Agree to avoid swimming, prolonged sun exposure, sauna, and steam baths during the study period; 6) Agree to discontinue the use of any other cleansing and skincare products on the forearm during the study period; 7) Willingness to read, write and sign an informed consent form to demonstrate willingness and ability to participate; 8) Willingness to comply with all requirements of the research protocol; 9) Have no reason assessed by the investigators as unsuitable for participation in the testing; 10) Intends to complete the study and is willing and able to follow all study instructions. 11\) Subjects who could comply with standards during the whole study that refrain from the use of towel, bath ball or any other bath sponges on the forearm. Exclusion Criteria: * 1\) Undergoing dermatological treatment or those who have taken whitening or anti-aging dietary supplements within the past month; 2) Have allergies to skincare products, soap, alcohol, fragrances, or medications; 3) Have used antihistamines within the past week or immunosuppressants with…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Clinical Grading by Dermatologist

Timeframe: Day 1 to Day 22

Trial details

NCT IDNCT07154004

SponsorBEIJING YUANBEN INFORMATION CONSULTING CO., LTD

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2025-05-31

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