CompletedNot Applicable

Efficacy of Albumin Platelet Rich Fibrin on Complications After Mandibular Third Molar Extraction.

Egypt16 participantsStarted 2025-09-20

Plain-language summary

Sixteen patients with bilateral impacted lower third molars seeking treatment will be recruited from the out-patient clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry at Mansoura University.

Who can participate

Age range18 Years – 40 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy patients classified as ASA (American Society of Anesthesiologists) Physical Status Classification Class I. * Patients seeking extraction of both mandibular third molars. * Patients aged 18 - 40 years old by the day of surgery. * Patients willing to participate in the study and commit to regular follow-up appointments. Exclusion Criteria: * Heavy Smokers (more than 25 cigarettes per day). * Patients with Poor oral hygiene. * Patients with history of a chemotherapy or radiotherapy

What they're measuring

Assessment of Facial Swelling (Edema): in Centimeters

Timeframe: first day, third day and seventh day

Wound Healing: Disturbed/Not Disturbed

Timeframe: first day, third day and seventh day

Postoperative pain severity assessment : using a 10 point Visual Analogue Scale (VAS)

Timeframe: first day, third day and seventh day

Laboratory Assessments of multiple blood/Biochemical markers and their concentrations

Timeframe: first day, third day and seventh day

Trial details

NCT IDNCT07153133

SponsorMansoura University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-02-25

View on ClinicalTrials.gov More Tooth Extraction Site Healing trials