Efficacy of Combined Fractional Er:Glass and Thulium Lasers Versus Microneedling for Atrophic Acn… (NCT07151599) | Clinical Trial Compass
RecruitingNot Applicable
Efficacy of Combined Fractional Er:Glass and Thulium Lasers Versus Microneedling for Atrophic Acne Scars
Brazil84 participantsStarted 2025-10-16
Plain-language summary
The purpose of this study is to compare two treatments for acne scars on the face. The study will test whether fractional lasers (Erbium:Glass and Thulium) lead to better improvement in acne scars than microneedling.
Who can participate
Age range
18 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Fitzpatrick skin phototypes I to VI
* Presence of atrophic acne scars on the face
Exclusion Criteria:
* Decompensated systemic diseases
* Any active infection (e.g., viral such as herpes, bacterial, or fungal)
* Pregnant or breastfeeding women
* Presence of hypertrophic or keloid scars
* Current use of anticoagulant or antiplatelet medications
* History of hemophilia or coagulation disorders
* Current use of anti-inflammatory drugs or corticosteroids
* Use of retinoids, including isotretinoin, within the past 6 months
* Exposure to sunlight within the past 15 days
* Undergoing any aesthetic facial treatment or having undergone scar treatments in the facial region within 180 days prior to study initiation
* Presence of active acne (occasional isolated lesions will not be considered exclusion criteria)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
ECCA grading scale (échelle d'évaluation clinique des cicatrices d'acné)
Timeframe: Assessments will be performed by blinded evaluators using standardized photographs at baseline.
2
ECCA grading scale (échelle d'évaluation clinique des cicatrices d'acné)
Timeframe: Assessments will be performed by blinded evaluators using standardized photographs at 30 days after the last session.
3
ECCA grading scale (échelle d'évaluation clinique des cicatrices d'acné)
Timeframe: Assessments will be performed by blinded evaluators using standardized photographs at 16 weeks after the last session.