CompletedNot Applicable

Cuff Pressure and Airway Edema in CABG With CPB

Turkey (Türkiye)76 participantsStarted 2025-09-24

Plain-language summary

This study investigates how endotracheal tube (ETT) cuff pressure management during cardiopulmonary bypass (CPB) in coronary artery bypass grafting (CABG) affects upper airway edema. Patients will be randomized into two groups: cuff pressure kept at 0 mmHg or maintained at 20-30 mmHg during CPB. Ultrasonography will be used to measure lateral pharyngeal wall thickness, tongue parameters, and other airway dimensions at predefined perioperative time points. The primary outcome is the change in lateral pharyngeal wall thickness as an indicator of airway edema. A total of 76 patients aged 18-80 years undergoing elective CABG with CPB will be enrolled. The results aim to clarify safe cuff pressure management strategies to reduce airway edema.

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients scheduled for elective coronary artery bypass grafting (CABG) surgery * Aged 18-80 years * ASA physical status class III-IV * Providing written informed consent Exclusion Criteria: * History of difficult intubation * Anatomical abnormalities of the upper airway * Body mass index (BMI) \> 35 kg/m² * Acute respiratory tract infection * Emergency surgeries

What they're measuring

Change in Lateral Pharyngeal Wall Thickness Measured by Airway Ultrasound

Timeframe: T0: Preoperative T1: Before initiation of CPB T2: At the end of CPB T3: 2nd postoperative hour

Trial details

NCT IDNCT07148024

SponsorEngin Çetin

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2026-04-19

View on ClinicalTrials.gov More Airway Ultrasound trials