SL-START - SubLingual Apomorphine Schemes of TitrAtion in Real-world Treatment (NCT07145190) | Clinical Trial Compass
RecruitingNot Applicable
SL-START - SubLingual Apomorphine Schemes of TitrAtion in Real-world Treatment
Germany90 participantsStarted 2025-08-27
Plain-language summary
The purpose of the study is to generate real-world evidence data for the on-demand treatment with SL-APO, focusing on understanding its usage and titration practices including individual dose determination after dose-adjustment to ultimately understand their influence in patient satisfaction, treatment persistence, and the balance between effectiveness and safety. The data may help optimize titration approaches to better meet the patient's needs.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* The patient is ≥ 18 years of age.
* The patient has a clinical diagnosis of idiopathic Parkinson's disease.
* The patient will initiate SL-APO for the treatment of OFF episodes according to the SmPC.
* The patient is not currently on titration or maintenance dose for SL-APO.
* The patient has provided written informed consent to participate in this study.
Exclusion Criteria:
* The patient is participating in a clinical trial with an investigational drug.
* The patient has presented with dementia or evidence of cognitive decline as determined by the investigator.
* The patient has a history of psychotic disorder.
* The patient presents any other contraindication according to the SL-APO SmPC.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Identify the most frequent dose used after dose-adjustment