Not Yet RecruitingNot Applicable

"Evolution of Sexual Symptoms in Paraphilic Sexual Offenders With/Without Antiandrogen or SSRI Treatment"

200 participantsStarted 2025-09-15

Plain-language summary

The ESPARA study is a multicenter observational research project aiming to monitor, over a three-year period, the evolution of sexual symptoms in male sexual offenders with paraphilia, divided into three groups: receiving antiandrogen treatment, receiving selective serotonin reuptake inhibitors (SSRIs), or no pharmacological treatment. The primary objective is to assess changes in sexual desire intensity and deviant sexual behaviors, while secondary objectives include relapse rates, the role of psychiatric comorbidities, treatment tolerability, and various clinical, cognitive, and life-history factors.

Who can participate

Age range18 Years

SexMALE

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Inclusion Criteria: * Men suffering from paraphilias (DSM-5 criteria), * Aged 18 to 65 years, * Sexual offenders (offense or sexual assault including exhibitionism, rape, sexual touching, incest, possession of pedopornographic video material) (severity level 1 to 6 according to WFSBP recommendations), * Subject who has given consent, * Patients covered by social security, * Satisfactory command of written and spoken French." Exclusion Criteria: * Subject in prison (regardless of the reason), * Subject under guardianship (patients under legal supervision may, however, be included), * Subjects who have committed a sexual offense and do not meet the DSM-5 criteria for paraphilia."

What they're measuring

Change in sexual desire and paraphilic behavior scores using the Intensity of Sexual Desire and Sexual Symptoms Scale (ISDSS, self-report)

Timeframe: Baseline

Trial details

NCT IDNCT07144943

SponsorCentre Hospitalier St Anne

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2030-09

Contact for this trial

Florence THIBAUT, Professor

01 58411679 florence.thibaut@aphp.fr