RecruitingNot Applicable

Anastomotic Leakage After Colorectal Surgery.

Egypt430 participantsStarted 2025-08-25

Plain-language summary

Anastomotic leakage (AL) is a severe complication after colorectal surgery, with incidence rates of 2-30%. This prospective, single-center observational cohort study aims to identify and quantify independent risk factors for AL, determine its incidence and impact on outcomes, and develop a predictive model. Approximately 430 patients undergoing colorectal resection with anastomosis will be enrolled from August 2025 to August 2026. Risk factors will be assessed preoperatively, intraoperatively, and postoperatively. AL will be defined and graded per the International Study Group of Rectal Cancer (ISGRC) criteria.

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged ≥18 years * Undergoing elective or emergency colorectal resection with primary anastomosis (e.g., ileocolic, colocolic, colorectal, coloanal) * Providing written informed consent Exclusion Criteria: * Colorectal resection without anastomosis (e.g., end stoma) * Inflammatory bowel disease (Crohn's, ulcerative colitis) * History of previous colorectal surgery involving anastomosis * Pregnancy * Unable to provide informed consent or comply with follow-up

What they're measuring

Incidence of Anastomotic Leakage (AL)

Timeframe: Within 30 days post-surgery.

Trial details

NCT IDNCT07144683

SponsorMinia University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-08-25

Contact for this trial

Saleh K Saleh, MD

01201765401 salehkhairy@mu.edu.eg

View on ClinicalTrials.gov More Anastomotic Leak trials