Active — Not RecruitingNot Applicable

Fat Around Heart Arteries as a Measure of Inflammation in Patients With Glycometabolic Disease

Denmark747 participantsStarted 2016-03

Plain-language summary

In this study, the objective is to investigate inflammation in the arteries of the heart. A heart CT scan (CCTA) will be used to measure inflammation by assessing the fat tissue surrounding the arteries of the heart. Participants with and without type 2 diabetes who have no heart symptoms have been examined and had a CCTA scan performed. This study aims to answer the following questions: • Is inflammation in the surrounding fat tissue of the heart arteries associated with the following glycometabolic conditions: I) Obesity ii) Prediabetes iii) Type 2 diabetes

Who can participate

Age range18 Years

SexMALE

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Inclusion Criteria: * Above 18 years * Capable of giving written informed consent Exclusion Criteria: * History of CAD * Symtoms of CAD (angina) * Any tachyarrhythmias making CCTA impossible * Estimated glomerular filtration rate (eGFR) under 45 ml/min * Allergy to iodine contrast * Critical illness with life expectancy less than 1 year * Documented heart failure

What they're measuring

PCAT Attenuation [Hounsfield Units (HU)] measured by coronary CT angiography

Timeframe: Baseline

Trial details

NCT IDNCT07144670

SponsorOdense University Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-07-01

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